Signature RX

Pharmacy Supply Chain Solutions

WHAT WE DO

Signature RX is your trusted 503B outsource facility partner in pharmaceutical manufacturing.

We specialize in manufacturing a wide range of pharmaceutical compounds, as well as offer innovative contracting solutions to elevate your business to the next level.

ABOUT US ↓
OUR SERVICES

Discover the range of our personalized pharmaceutical services.

ALL SERVICES ↓

503A & 503B Solutions

Explore our innovative solutions with SIGNATURERX-503A, offering a swift response to critical drug shortages, and experience the operational SIGNATURERX-503B facility, dedicated to providing cost-effective, quality care.

Oral Formulations

Unlock a world of oral healthcare innovation with our diverse formulations, including tablets, capsules, suspensions, solutions, SL tablets, SR capsules, troches, lollipops, sub-linguals and more.

Topical Formulations

Dive into a realm of skincare ingenuity with our trans-dermal creams, topical creams, gels, ointments, PLO gels, kits, packs and patches.

Injectables

Explore our wide variety of injectables, including IVs, subcutaneous, intramuscular, vaginal formulations, rectal formulations and more.

Click on the button below to view the current FDA drug shortages

Current FDA Drug Shortages ↓

OUR PROACTIVE APPROACH

At Signature RX, we proactively address drug shortages, ensuring consistent access to vital medications. By staying vigilant and aligning our practices with the FDA guidelines, we work to anticipate and respond to drug shortages promptly.

MEET OUR TEAM

David Hughes

David Hughes, PharmD,

R.Ph., ABAAHP, PAHM
Chief Executive Officer & Head Chemist
Christopher S. Musser

Christopher S. Musser

R.Ph., PMP, LSSBB
Chief Pharmacy Officer
Dr. Anita Stateng

Dr. Anita Stateng

Pharmaceutical Formulation Lead
Jaime Cortez Jr.

Jaime Cortez Jr.

Sterile Processing Technician
ABOUT US

Introducing an Innovative Solution

Blending 503b and 503a Strategies to Tackle Drug Supply Chain Challenges for Health Systems.

In November 2013, President Barack Obama signed the Compounding Quality Act (DQSA), mandating the compounding industry to adhere to specific guidelines ensuring the safety and quality of their prepared products. The emergence of 503b Outsourcing facilities was a pivotal development, playing an integral role in the hospital drug supply.

However, existing registered 503b outsourcing facilities fall short of meeting the immediate demands of health systems during drug shortages. Allocations and limited facility capacity often hinder a rapid response to critical shortages, causing disruptions in patient care reported by hospitals nationwide.

Currently, only 73 registered 503b outsourcing facilities cater to over 6,000 hospitals in the U.S. These facilities, with their limited production capacities, predominantly focus on repackaging non-patient specific medications for health systems, neglecting to pivot and address critical drug shortages.

OUR CUSTOMER COMPANIES

We are an orchestrated alliance of companies, featuring PharmaPac, SignatureRX, and BKG Medical Supplies. Each entity plays a unique yet interconnected role, ensuring a seamless and impactful healthcare experience for professionals and patients alike.

Signature RX leads in healthcare innovation by providing solutions for health systems, particularly during drug shortages and supply chain challenges. The SignatureRX-503B facility responds promptly to critical drug shortages, ensuring quality care and cost savings for health-system partners. The SignatureRX-503A program offers an emergency contingency plan, maintaining compliance with FDA regulations. Additionally, Signature RX compounds dosages for oral formulations, topical formulations, and injectables.

OUR SERVICES

We Offer a Range of Services to Meet Your Needs

The Signature RX Solution

Signature RX provides comprehensive pharmaceutical compounding services for health systems across the country. Our state-of-the-art 503B outsourcing facility and complementary 503A program allow us to respond swiftly to drug shortages while maintaining the highest quality standards.

We work directly with health systems to deliver customized solutions that address their unique supply chain challenges, ensuring uninterrupted patient care at competitive costs.

Our Capabilities

Signature RX compounds the following dosage forms:

Oral Formulations

Tablets, capsules, suspensions, solutions, SL tablets, SR capsules, troches, lollipops, sub-linguals

Topical Formulations

Trans-dermal creams, topical creams, gels, ointments, PLO gels, kits, packs, patches

Injectables

IVs, subcutaneous, intramuscular, vaginal formulations, rectal formulations

News & Updates

March 2026

Signature RX Expands 503B Capabilities

Signature RX continues to invest in expanded compounding capabilities at our Delray Beach facility, addressing growing demand from health system partners nationwide.

February 2026

Addressing Critical Drug Shortages

Our proactive approach to FDA-listed drug shortages ensures health systems maintain access to essential medications for patient care continuity.

January 2026

New Formulation Development

Signature RX announces expanded oral and injectable formulation options to better serve our health system partners.

Contact us

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